Ziyuan Li (李子元), Ph. D.
E-Mail: schmeichel_lee@163.com
liziyuan@bjmu.edu.cn
Tel: 0086-010-82805294
Born: April 21st, 1984, Chengdu, China PR
Lab: Room 205 in Building 3
Education
2010.9 – 2013.6 China Pharmaceutical University Ph. D. in medicinal chemistry
(with Prof. Hequan Yao and Prof. Xiaoming Wu)
2006.9 – 2010.6 China Pharmaceutical University M. Sc. in medicinal chemistry
(with Prof. Hequan Yao and Prof. Xiaoming Wu)
2002.9 – 2006.6 Sichuan University B. Sc. in biotechnology
Publications
1. Ziyuan Li, Ling Ma, Jinyi Xu, Lingyi Kong, Xiaoming Wu, Hequan Yao*. Pd(II)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage. Chem. Commun. 2012, 48(31), 3763-3765.
2. Ziyuan Li, Haipin Zhou, Xiaoming Wu*, Hequan Yao*. Advances in chemical synthesis of structurally modified bioactive RNAs. Curr. Med. Chem. 2013, 20, in press.
3. Ziyuan Li, Yiyun Wang, Yue Huang, Changhua Tang, Jinyi Xu, Xiaoming Wu*, Hequan Yao*. Efficient palladium(II)-catalyzed homocoupling of thiazole-4-carboxylic or oxazole-4-carboxylic derivatives.Tetrahedron 2011, 67(31), 5550-5555.
4. Ziyuan Li,Haiping Zhou, Jinyi Xu, Xiaoming Wu, Hequan Yao*.Aryl-aryl coupling via palladium-catalyzed C-P/C-H bond cleavage. Tetrahedron 2013, 69(15), 3281-3286.
5. Ziyuan Li,Ling Ma, Chuanghua Tang, Jinyi Xu, Xiaoming Wu, Hequan Yao*.Palladium(II)-catalyzed oxidative Heck coupling of thiazole-4-carboxylates. Tetrahedron Lett. 2011, 52(43), 5643-5647.
6. Lei Zhao, Ziyuan Li, Lin Chang, Jinyi Xu, Hequan Yao*, Xiaoming Wu*. Efficient construction of fused indolines with a 2-quaternary center via an intermolecular Heck reaction with a low catalyst loading.Org. Lett. 2012, 14(8), 2066-2069.
7. Yiyun Wang, Ziyuan Li, Yue Huang, Changhua Tang, Xiaoming Wu, Jinyi Xu*, Hequan Yao*. Copper(II)-catalyzed oxidation of 4-carboxythiazolines and 4-carboxyoxazolines to 4-carboxythiazoles and 4-carboxyoxazoles. Tetrahedron 2011, 67(38), 7406-7411.
8. Guangling Zhang, Ziyuan Li, Yue Huang, Jinyi Xu, Jinyi Xu, Hequan Yao*. Direct C3-alkenylation of pyridine-4(1H)-one via oxidative Heck coupling. Tetrahedron 2011, 69(3), 1115-1119.
9. Changhuang Tang, Ziyuan Li, Yiyun Wang, Jinyi Xu, Lingyi Kong, Xiaoming Wu*, Hequan Yao*.First total synthesis of tenuifolin via PIFA mediated oxidative biaryl coupling. Tetrahedron Lett. 2011,52(26), 3275-3278.
10. Lijun Ni, Ziyuan Li, Fan Wu, Jinyi Xu, Xiaoming Wu, Lingyi Kong, Hequan Yao*.Concise total syntheses of Marinoquinolines A-C. Tetrahedron Lett. 2012, 53(10), 1271-1274.
Academic Activities
(1) Construction and C5-Functionalization of Azole-4-carboxylate and Azole-4-formamide, The 19th International Conference on Organic Synthesis (ICOS-19), Speech,Melbourne, Australia, July 2012.
(2) Ar3P as Novel Aryl Donor in Palladium-Catalyzed Aryl-aryl Coupling, The 17th National Symposium on Organometallics, Poster,Beijing, China, Oct. 2012.
(3) C5 Cross-coupling of Thiazole/oxazole-4-carboxylic Derivatives Through Double C-H Bond Cleavage, The 28th Congress of the Chinese Chemical Society, Poster,Chengdu, China, Apr. 2012.
Awards
National Award for Graduate Students (2012).
President Award of China Pharmaceutical University (2012).
Bright Future® Pharmaceutics Award (2012).
Sanhome® Award for Innovative Outcomes of Graduate Research (2011, 2012).