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Name: |
Xinyao LI M/F: Male |
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Date of Birth: |
10th March, 1988 Nationality: China |
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Affiliation: |
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China |
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Phone: |
(+86) 13810168454 |
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E-mail: |
xinyaoli@pku.edu.cn |
Educational Background
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2013.9 - 2016.7 |
Ph. D. in Medicinal Chemistry, Peking University, Beijing, China |
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2007.9 - 2013.7 |
B. S. and M. S. in Organic Chemistry, Beijing University of Chemical Technology, Beijing, China |
Research Experience
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2017.9 - now |
Postdoctor, Supervisor: Prof. Thorsten Bach, Technische Universität München |
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2016.8 - 2017.7 |
Research assistant, Peking University |
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2013.8 - 2016.7 |
Ph. D., Supervisor: Prof. Ning Jiao, Peking University |
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2009.8 - 2013.7 |
B. S. and M. S., Supervisor: Prof. Jiaxi Xu, Beijing University of Chemical Technology |
Honors & Awards
l Humboldt Research Fellowship for Postdoctoral Researchers, in 2017
l National Scholarship for Postgraduate/Graduate students, in 2015.
l Peking University Innovation Award, in 2015.
l Learning Outstanding Individual Awards, 2014
l Outstanding graduates in Beijing, in 2013.
l National Scholarship for Postgraduate/Graduate students, in 2012.
Selected Publication List
1. Li, X. Y.; Li, X. W.; Jiao, N. Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C−H Bond Activation of Simple Anilines with CO and Alkynes. J. Am. Chem. Soc. 2015, 137, 9246−9249.
2. Li, X. Y.; Pan, J.; Song, S.; Jiao, N. Pd-catalyzed Dehydrogenative Annulation Approach for the Efficient Synthesis of Phenanthridinones. Chem. Sci. 2016, 7, 5384−5389.
3. Li, X. Y.; Pan, J.; Wu, H.; Jiao, N. Rh-catalyzed Aerobic Oxidative Cyclization of Anilines, Alkynes, and CO. Chem. Sci. 2017, DOI: 10.1039/c7sc02181j.
4. Liang, Y.-F.;† Li, X. Y.;† Wang, X. Y.; Zou, M. C.; Tang, C. H.; Liang, Y. J.; Song, S.; Jiao, N. Conversion of Simple Cyclohexanones into Catechols. J. Am. Chem. Soc. 2016, 138, 12271−12277. (†Y.-F.L. and X.L. contributed equally.)
5. Sun, X.;† Li, X. Y.;† Song, S.; Zhu, Y. C.; Liang, Y. F.; Jiao, N. Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to β-Azido Alcohols. J. Am. Chem. Soc. 2015, 137, 6059−6066. (†X.S. and X.L. contributed equally.)
6. Chen, F.;† Huang, X. Q.;† Li, X. Y.;† Shen, T.; Zou, M. C.; Jiao, N. Dehydrogenative N-Incorporation: A Direct Approach to Quinoxaline N-Oxides under Mild Conditions. Angew. Chem. Int. Ed. 2014, 53, 10495–10499. (†C.F., X.H., and X.L. contributed equally.)
7. Huang, X. Q.; Li, X. Y.;, Zou, M. C.; Song, S.; Tang, C. H.; Yuan, Y. Z.; Jiao, N. From Ketones to Esters by a Cu-Catalyzed Highly Selective C(CO)-C(alkyl) Bond Cleavage: Aerobic Oxidation and Oxygenation with Air. J. Am. Chem. Soc. 2014, 136, 14858−14865.
8. Huang, X. Q.; Li, X. Y.; Jiao, N. Copper-catalyzed Direct Transformation of Simple Alkynes to Alkenyl Nitriles via Aerobic Oxidative Nincorporation. Chem. Sci. 2015, 6, 6355−6360.
9. Liang, Y. F.; Li, X. Y.; Wang, X. Y.; Yan, Y. P.; Feng, P.; Jiao, N. Aerobic Oxidation of PdII to PdIV by Active Radical Reactants: Direct C−H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen. ACS Catal. 2015, 5, 1956−1963.
10. Zhu, Y. C.; Li, X. Y.; Wang, X.; Huang, X.; Shen, T.; Zhang, Y.; Sun, X.; Song, S.; Jiao, N. Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids. Org. Lett. 2015, 17, 4702−4705.
11. Liu, J. Z.;† Wen, X. J.;† Qin, C.;† Li, X. Y.; Luo, X.; Sun, A.; Zhu, B.; Song, S.; Jiao, N. Oxygenation of Simple Olefins via Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes, Angew. Chem. Int. Ed. 2017, .
12. Li, X. W.; Lin, F.; Huang, K.; Wei, J.; Li, X. Y.; Wang, X.; Geng, X.; Jiao, N. Selective α-Oxyamination and Hydroxylation of Aliphatic Amides. Angew. Chem. Int. Ed. 2017, DOI: 10.1002/anie.201706963.
13. Li, X. Y.;† Jin, X.;† Xu, J. X. Annuloselectivity in Reactions of Diacyl Dichlorides and Imines: Combined Experimental and Theoretical Studies. J. Org. Chem. 2015, 80, 6976−6985. (†X.L. and X.J. contributed equally.)
14. Hou, S.;† Li, X. Y.;† Xu, J. X. N[1,3]-sigmatropic Shift in the Benzidine Rearrangement: Experimental and Theoretical Investigation. Org. Biomol. Chem. 2014, 12, 4952−4963. (†S.H. and X.L. contributed equally.)
15. Li, X. Y.; Xu, J. X. DFT and Experimental Exploration of Intramolecular [2 + 2 + 2] Cycloaddition of Oxanorbornadienedicarboxylates and Analogues. J. Org. Chem. 2013, 78, 3039−3047.
16. Li, X. Y.; Xu, J. X. Annuloselectivity in Cycloadditions of Ketenes with Imines: A DFT Study. J. Org. Chem. 2013, 78, 347−355.
17. Li, X. Y.; Yang, Z. Y.; Xu, J. X. Comprehensive Theoretical Investigation on the Regioselectivity in the Nucleophilic Ring Opening of Epoxides. Curr. Org. Synth. 2013, 10, 169–177.
18. Li, X. Y.; Xu, J. X. Theoretical insights into the [4 + 2]/retro [4 + 2] cycloaddition approach to the synthesis of biaryls and polycyclic aromatics. Sci. China Chem. 2013, 56, 633–640.
19. Li, X. Y.; Xu, J. X. Theoretical Insights into the Metal-free and Formal [2 + 2 + 2] Cycloaddition Strategy via Intramolecular Cascade Propargylic ene/Diels–Alder Reactions with Tautomerization. Org. Biomol. Chem. 2011, 9, 5997–6003.
20. Qi, H. Z.;† Li, X. Y.;† Xu, J. X. Stereoselective Control in the Staudinger Reactions Involving Monosubstituted Ketenes with Electron Acceptor Substituents: Experimental Investigation and Theoretical Rationalization. Org. Biomol. Chem. 2011, 9, 2702–2714. (†H.Q. and X.L. contributed equally.)
21. Li, X. Y.; Xu, J. X. Theoretical Calculational Investigation on the Regioselectivity of the Ring Opening of Thiiranes with Ammonia and Amines.Tetrahedron 2011, 67, 1681–1688.
22. Li, X. Y.; Xu, J. X. Abundant Intramolecular Ring Rearrangements of 1-(N-Benzyloxycarbonylamino)arylmethylphosphonate Phenyl monoesters Under Electrospray Ionization Conditions. Phosphorus, Sulfur, and Silicon, 2011, 186, 503–510.
23. Li, X. Y.; Chen, N.; Xu, J. X. An Improved and Mild Wenker Synthesis of Aziridines.Synthesis 2010, 20, 3423–3428.