E-mail:15210009800@163.com
毕业去向:
巢生(北京)创业投资管理有限公司
教育经历:
2013.9-2017.6 北京大学医学部 药学院 学士
2017.9-2019.6 北京大学医学部 药学院 化学生物学系 硕士,导师:周德敏 教授
2019.9-2022.6 北京大学医学部 药学院 临床药学系 博士,导师:周德敏 教授
研究领域:
基于PTC病毒的新型抗流感病毒策略
流感病毒的快速检测和纯化方法
核酸药物抗新冠病毒新方法
荣誉奖励:
北京大学医学部博士生创新人才(2021)
北京大学优秀科研奖(2021)
北京大学优秀毕业生(2022)
科研成果:
1.Wenxiao Ma, Boyang Cheng, Longlong Si, Zefeng Guo, Yi Chen, Xinchen Wang, Dezhong Ji, Weixuan Zhao, Xueying Zhou, Zhenyu Tian, Simo Liu, Han Bao, Qi Wang, Sulong Xiao, Chuanling Zhang, Qing Xia, Lihe Zhang, Demin Zhou. Synergizing Genomic Shuttling of Nonsense Mutations and Existing Antivirals as a Biotherapeutic for Infecting Flu Viruses. Cell Chemical Biology, 2022, under review.
2. Su X†, Ma W†, Feng D, Cheng B, Wang Q, Guo Z, Zhou D, Tang X. Efficient Inhibition of SARS-CoV-2 Using Chimeric Antisense Oligonucleotides through RNase L Activation*. Angew Chem Int Ed Engl. 2021 Sep 27;60(40):21662-21667.
3.Li G†, Ma W†, Mo J, Cheng B, Shoda SI, Zhou D, Ye XS. Influenza Virus Precision Diagnosis and Continuous Purification Enabled by Neuraminidase-Resistant Glycopolymer-Coated Microbeads. ACS Appl Mater Interfaces. 2021 Oct 6;13(39):46260-46269.
4.Li, H., Wang, S., Ma, W., Cheng, B., Yi, Y., Ma, X., Xiao, S., Zhang, L., & Zhou, D. (2022). Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders. Journal of medicinal chemistry, 10.1021/acs.jmedchem.1c02013. Advance online publication.
5.Zhang B, Sun J, Wang Y, Ji D, Yuan Y, Li S, Sun Y, Hou Y, Li P, Zhao L, Yu F, Ma W, Cheng B, Wu L, Hu J, Wang M, Song W, Li X, Li H, Fei Y, Chen H, Zhang L, Tsokos GC, Zhou D, Zhang X. Site-specific PEGylation of interleukin-2 enhances immunosuppression via the sustained activation of regulatory T cells. Nat Biomed Eng. 2021 Nov;5(11):1288-1305.
6.Zhang B, Wang Y, Huang S, Sun J, Wang M, Ma W, You Y, Wu L, Hu J, Song W, Liu X, Li S, Chen H, Zhang G, Zhang L, Zhou D, Li L, Zhang X. Photoswitchable CAR-T Cell Function In Vitro and In Vivo via a Cleavable Mediator. Cell Chem Biol. 2021 Jan 21;28(1):60-69.e7.
7.Li M, Yuan L, Chen Y, Ma W, Ran F, Zhang L, Zhou D, Xiao S. Rhodamine B-based fluorescent probes for molecular mechanism study of the anti-influenza activity of pentacyclic triterpenes. Eur J Med Chem. 2020 Nov 1;205:112664.
8.马闻箫, 程博洋, 周德敏. 疫苗研发: 新技术应获更多重视. 前沿科学, 2020, (2): 56-62.
9.周雪莹, 马闻箫, 周德敏. 活病毒直接转化为预防、治疗双功能疫苗研究进展. 中国科学基金, 2018, 32(05): 485-490.
座右铭:
所有感恩应该用努力回报