自定义
Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Functional characterization of two efficient glycosyltransferases catalysing the formation of rutin from Sophora japonica L. Regio-specific enzymatic glucosylation of triterpenoids from Antrodia camphorata and their biological activities. Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus. Licorice-saponin A3 is a broad-spectrum inhibitor for COVID-19 by targeting viral spike and anti-inflammation. Identification of oxidosqualene cyclases associated with saponin biosynthesis from Astragalus membranaceus reveals a conserved motif important for catalytic function. Collaborative modification strategy to develop a highly selective fluorescent probe for human UDP-glucuronosyltransferase 1A10. Xinfang Zhai, et al. Chemical Engineering Journal. 2023.   Functional characterization, structural basis, and regio-selectivity control of a promiscuous flavonoid 7,4′-di-O-glycosyltransferase from Ziziphus jujuba var. spinosa. Zi-long Wang, et al. Chem Sci. 2023. GuRhaGT, a highly specific saponin 2′′-O-rhamnosyltransferase from Glycyrrhiza uralensis. Zilong Wang, et al. Chem Commun. 2022.  Advances in plant-derived C-glycosides: Phytochemistry, bioactivities, and biotechnological production. Yaqun Zhang, et al. Biotechnol. Adv. 2022. A highly selective 2''-O-glycosyltransferase from Ziziphus jujuba and De novo biosynthesis of isovitexin 2''-O-glucoside. Yaqun Zhang, et al. Chem. Commun. 2022. Functional characterization of a C-glycosyltransferase from Pueraria lobata with dual-substrate selectivity. Yang-oujie Bao, et al. Chem. Commun. 2022. Functional Characterization and Protein Engineering ofaTriterpene 3-/6-/2’-O-Glycosyltransferase Reveal aConserved Residue Critical fortheRegiospecificity. Meng Zhang, et al.  Angew. Chem., Int. Ed. 2022. Natural triterpenoids from licorice potently inhibit SARS-CoV-2 infection. Yang Yi, et al. J. Adv. Res. 2022. Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.Yang Yi, et al. Acta Pharm. Sinica B. 2022. Rational design of a highly selective UGT1A1 probe and its application in drug discovery. Xinfang Zhai, et al. Sens. Actuators B Chem. 2022. Terpenoids from the medicinal mushroom Antrodia camphorate: chemistry and medicinal potential. Yi Kuang, et al. Nat. Prod. Rep. 2021. Characterization of a highly selective 2²-O-galactosyltransferase from Trollius chinensis and structure-guided engineering for improving UDP-glucose selectivity. Shuang Liu, et al. Org. Lett. 2021.  Dissection of the general two-step di-C-glycosylation pathway for the biosynthesis of (iso)schaftosides in higher plants. Zi-long Wang, et al. Proc. Natl. Acad. Sci. U. S. A. 2020.  Functional characterization and structural basis of an efficient di-C-glycosyltransferase from Glycyrrhiza glabra. Meng Zhang, et al. J. Am. Chem. Soc. 2020.
 1 2 下一页